Weakly hydrated anions help to solubilize hydrophobic macromolecules in aqueous solutions, but small molecules comprised of the same chemical constituents precipitate out when exposed to these ions. Herein, this apparent contradiction is resolved by systematically investigating the interactions of NaSCN with polyethylene oxide oligomers and polymers of varying molecular weight. A combination...
Dynamical factors controlling hopping speed and efficiency in two modified azurin constructs that include a rhenium(I) sensitizer, Re(His)(CO)3(dmp)+, one or two tryptophans (W1, W2) and CuI center were studied by femtosecond time-resolved spectroscopy. Experimental kinetics investigations showed that the two closely spaced (3-4 Å) intervening tryptophans dramatically accelerated long-range...
Ribosomes are complex biomachines responsible for protein synthesis in all organisms. The ribosome consists of three strands of RNA and dozens of ribosomal proteins. It is organized into two subunits, where the small subunit reads the mRNA and the large subunit catalyzes peptide bond formation. The nascent protein translocates from the catalytic center to the ribosome surface through a 10...
