Ribosome is a huge biomolecular complex responsible for protein synthesis in all living organisms. As a multi-component system consisting of several strands of RNA and a few dozen proteins, the ribosome is particularly challenging for current molecular dynamics simulations [1]. In the past few years, we carried out many atomistic computer simulations of the entire ribosome in explicit aqueous...
Phylogenomics has proven to be indispensable for inferring the eukaryotic tree of life. During the ongoing project, we are using Phylofisher software for proper ortholog detection, contamination removal, and reconstruction of phylogenetic relationships within the neglected eukaryotic major group Heterolobosea. This group contains free-living as well as facultatively parasitic microbial...
